Joshua L. Roffman


Principal Investigator

Joshua L. Roffman MD, MMSc is an Associate Professor of Psychiatry at Harvard Medical School, Co-Director of both Psychiatric Neuroimaging and Neuroscience at Massachusetts General Hospital (MGH), and Director of Research for the MGH Schizophrenia Clinical and Research Program.  He received his BA (neuroscience) from Amherst College, MD from the University of Maryland School of Medicine, and MMSc from Harvard Medical School.  Following  residency training in adult psychiatry at MGH and McLean Hospital and postdoctoral training in brain imaging and genetics at MGH, he established the Brain Genomics Laboratory within the MGH Department of Psychiatry, a multidisciplinary research program that merges imaging (MRI, PET), genomics, and clinical trials.  His current work, which is supported by NIMH, MQ: Transforming Mental Health, and NARSAD/Brain and Behavior Research Foundation, focuses on folate-based interventions and altered dopamine signaling in schizophrenia.

Hamdi Eryilmaz



Hamdi received his bachelor’s degree in Electrical Engineering (2004) and his masters in Biomedical Engineering (2007) in Turkey. He then completed his doctorate in neuroscience at University of Geneva, Switzerland (2012), where he investigated lasting effects of specific emotions on spontaneous brain activity and specialized in fMRI signal processing and functional connectivity. He had postdoctoral training with Prof. Randy Buckner at Harvard University Center for Brain Science (2012-2013),  joined the Roffman Lab in October 2013, and became an instructor at Harvard Medical School in 2018. His research focuses on neural underpinnings of working memory and reinforcement learning deficits in schizophrenia patients.

Dylan Hughes

Staff Assistant

Dylan graduated from the University of Massachusetts Boston in 2018, where he attained a BS in Psychology. During his time at UMass, his research focused on social perception, specifically the effect of various factors on perception of emotion in others. In the Brain Genomics Laboratory, Dylan assists with various research projects, and administrates the Translational Neuroscience Training for Clinicians post-doctoral fellowship.

Casey Hopkinson

Clinical Research Coordinator

Casey graduated from Northeastern University in 2019, majoring in Behavioral Neuroscience with a minor in Criminal Justice. Casey’s undergraduate research focused on the behavioral and physiological effects of stress on the relationships between mothers and their infants. In the Brain Genomics Laboratory, Casey is involved in various aspects of ongoing neuroimaging and genetic studies, including the recruitment of study participants as well as data collection and analysis.

Rachel Pride

Senior Research Coordinator

Rachel Pride, MPH is a recent graduate of the Columbia University Mailman School of Public Health Department of Population and Family Health where she focused in sexuality, sexual, and reproductive health. While at Columbia, she supervised a team of students making calls to pregnant patients at the height of the COVID pandemic for the COVID-19 Student Services Corps. Research she worked on during grad school included a study at the Teachers College linking early adversity and brain and language development in the first years of life and a study looking at adolescent attitudes towards HIV testing in the pediatric emergency department, and her thesis examined barriers to reproductive justice in system-involved youth. She earned her BS in Neuroscience from DePaul University in Chicago, where she focused on physiological stress associated with poverty and racism and its impacts on neurodevelopment. Currently, she is working with Dr. Roffman and co-investigators to launch the Brain Health Begins Before Birth (B4) study, a hospital-wide birth cohort study examining pandemic-related, in utero risk and protective factors to adverse neurodevelopmental outcomes. Within MGH, she is also a volunteer birth doula with the Birthing Gently Maternal Health Program.


Randy Buckner, Ph.D.

Daphne Holt, MD, Ph.D.

Dara Manoach, Ph.D.

Jordan Smoller, MD, Sc.D.

Jacob Hooker, Ph.D.

Roy Perlis, MD, M.Sc.

Hannah Brown, MD

Erin Dunn, Sc.D., MPH

Rakesh Karmacharya, MD, Ph.D.

Alysa Doyle, Ph.D.

Lab Alumni

Eren Sipahi – Medical student, Michigan State Medical School

Kevin Dowling – MD/Ph.D candidate, University of Pittsburgh & Carnegie Mellon University MSTP

Gianni Petrozzino – Medical student, Rutgers Robert Wood Johnson Medical School

Tali Sorets – Undergraduate student at Brown University

Thomas Soare – Senior scientist, Goldfinch Bio

Anais Rodriguez-Thompson – Ph.D candidate in Clinical Psychology, University of North Carolina at Chapel Hill

Charlie Huntington – Ph.D candidate in Clinical Child Psychology, University of Denver

Alexandra Tanner – Ph.D candidate in Clinical Psychology, University of California-Los Angeles

Maddie Giegold – Medical student, Emory University

Daniel Cummings – Research assistant, Fenway Institute

Noah Silverstein – MD/Ph.D candidate, University of Massachusetts Medical School

New Fei Ho – Researcher at the Institute of Mental Health, Singapore

Adam Nitenson – Director of the State Targeted Response to the Opiod Crisis, Rhode Island Department of Behavioral Health

David Brohawn – Senior pathology specialist, Virginia Commonwealth University Molecular Diagnostics Laboratory